B-24 | Periprocedural Mortality in Chronic Total Occlusion Percutaneous Coronary Intervention: Insights from the PROGRESS-CTO Registry

Death is a rare but devastating complication of chronic total occlusion (CTO) percutaneous coronary intervention (PCI). We examined the clinical characteristics and procedural outcomes patients who died periprocedurally in Prospective Global Registry for Study CTO Intervention (PROGRESS-CTO, NCT02061436). Of 12,928 underwent PCI between 2012 2022, 52 (0.4%) during index hospitalization. Patients were more likely to have history heart failure (43% vs. 28%, p=0.023). The J-CTO (2.8 ± 1.1 vs 2.4 1.3, p=0.019), PROGRESS-CTO mortality (2.6 0.9 1.6 1.1, p<0.001), pericardiocentesis (2.9 1.9 p<0.001) scores higher died. In these patients, use left ventricular assist devices was (41% 3.5%, p<0.00), retrograde crossing often first strategy (33% 13%, p<0.001). cause death cardiac 43 (83%) non-cardiac 9 (17%). Complications leading were: tamponade 30 (58%), acute myocardial infarction (17.3%), arrest/shock 4 (7.7%). Non-cardiac causes stroke 3 (5.8%), renal 2 (3.8%), respiratory distress hemorrhagic shock (3.8%) (Figure). Approximately 0.4% main 58%. might help risk stratification planning undergoing PCI.